Hentschel is a Germanic surname. People with this surname include:
Carl Hentschel (1864–1930), British artist, photographer, printmaker, inventor and businessperson, and the original of "Harris" in Jerome K. Jerome's Three Men in a Boat (1889) Dan Hentschel (born 1996), American comedian and satirist David Hentschel (born 1952), English recording engineer, writer and music producer Erwin Hentschel (1917–1944), German Knight's Cross recipient Falk Hentschel (born 1982), German actor Franziska Hentschel (born 1970), German field hockey player Holger Hentschel (born 1985), German politician Johannes Hentschel (1908–1982), German master electro-mechanic Klaus Hentschel (born 1961), German historian of science Trent Hentschel (born 1982), Australian rules footballer York Hentschel (born 1953), Canadian football player