Deford may refer to:
People Surnames Frank Deford (1938–2017), American sportswriter and commentator Jelly Roll (singer) (born as Jason Bradley DeFord 1984), American rapper Miriam Allen deFord (1888–1975), American writer William DeFord (1807–1898), American politician from Ohio
Given names DeFord Bailey (1899–1982), early country music star and the first African American performer on the Grand Ole Opry
Places Deford, Michigan, United States, a community in Tuscola County