Ephedra holoptera is a species of Ephedra that is native to Iran.

It was originally described by Harald Udo von Riedl in 1963. It has been placed in section Alatae.Price, R. A. (1996). Systematics of the Gnetales: A review of morphological and molecular evidence. International Journal of Plant Sciences, 157(6): S40-S49.

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