Domina may refer to:
Female form of Dominus (title) Domina (grape), a type of grape Domina (Image Comics), a character of the Spawn comic book series Domina (TV series), a 2021 UK historical-drama television series Domina (video game), a gladiator management game by DolphinBarn Domina, one of the Neo (Marvel Comics species) Domina (Overwatch), a character in the Overwatch franchise. Domina a synonym for the fly genus Psilopa
People with the surname David Domina (born 1950), American politician
See also Dominia (disambiguation) Dominatrix