The Moses Morse House is a historic house in Methuen, Massachusetts, USA. It is a rare surviving farmhouse in the town with 18th century origins, with its oldest elements dating to c. 1762. It is a 2½ story wood-frame house with a massive central chimney, and a small single story ell on the left side. The ell appears to date from near the house's original construction, and the chimney is slightly off-center, indicating the house may have been built in stages. The front door is sheltered by an elaborate Italianate portico that is a c. 1870s modification.

The house was listed on the National Register of Historic Places in 1984.

See also National Register of Historic Places listings in Methuen, Massachusetts National Register of Historic Places listings in Essex County, Massachusetts

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