TLR may refer to:
Biology Toll-like receptors, proteins of the immune system Tonic labyrinthine reflex, in newborn humans
Travel Suzuki TL1000R motorcycle The IATA airport code for Mefford Field, California, USA The ICAO airline code for Air Libya, Libya
Other Twin-lens reflex camera Tasteful Licks Records Tony La Russa Terra Lawson-Remer