E100 or E-100 may refer to:
Electronics Casio Cassiopeia E-100, a pocket-size PC iRiver E100, a portable media player
Vehicles Automobiles Baojun E100, a Chinese electric microcar JMEV E100, a Chinese electric city car Toyota Corolla (E100), a Japanese compact car lineup
Military vehicles Panzerkampfwagen E-100, a proposed German World War II super-heavy tank
Other uses Curcumin, food coloring from turmeric designated by E number E100 Neat ethanol fuel, or E100, a fuel blend with almost 100% ethanol