A pituitary disease is a disorder primarily affecting the pituitary gland. __TOC__
Table The main disorders involving the pituitary gland are:
Condition Direction Hormone Acromegaly overproduction growth hormoneGigantismoverproductiongrowth hormone Cushing's disease overproduction adrenocorticotropic hormone Growth hormone deficiency underproduction growth hormone Syndrome of inappropriate antidiuretic hormone overproduction vasopressin Diabetes insipidus (can also be nephrogenic) underproduction vasopressin Sheehan syndrome underproduction any pituitary hormone Pickardt-Fahlbusch Syndrome underproduction any pituitary hormone, except prolactin, which is increased Hyperpituitarism (most commonly pituitary adenoma) overproduction any pituitary hormone Hypopituitarism underproduction any pituitary hormone
Overproduction or underproduction of a pituitary hormone will affect the respective end-organ. For example, insufficient production (hyposecretion) of thyroid stimulating hormone (TSH) in the pituitary gland will cause hypothyroidism, while overproduction (hypersecretion) of TSH will cause hyperthyroidism. Thyroidisms caused by the pituitary gland are less common though, accounting for less than 10% of all hypothyroidism cases and much less than 1% of hyperthyroidism cases.Page 358 in: Thyrotropin (TSH)-secreting pituitary adenomas. By Roy E Weiss and Samuel Refetoff. Last literature review version 19.1: January 2011. This topic last updated: July 2, 2009
See also Hypophysitis, inflammation of the pituitary gland. Autoimmune hypophysitis (or lymphocytic hypophysitis), inflammation of the pituitary gland due to autoimmunity. Nelson's syndrome, may occur after surgical removal of both adrenal glands, an out-dated method of treating Cushing's disease. Pituitary tumour, a tumor of the pituitary gland. Pituitary adenoma, a noncancerous tumor of the pituitary gland. Pituicytoma, a rare brain tumor. Pituitary apoplexy, bleeding into or impaired blood supply of the pituitary gland.
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