The Combahee Bank Lighthouse is a former lighthouse in St. Helena Sound on the border of Beaufort and Colleton Counties in South Carolina. It was built in 1868 and abandoned around 1876.Clary, Margie Willis, The Beacons of South Carolina, Sandlapper Publishing Co., Inc., Orangeburg, SC, 2005, pp. 102-103, .

The lighthouse was a cottage-style screwpile lighthouse that was built to warn of shoals. It was near the location of the current automated light, which is on a dolphin.

In 1902, a daymark was put on the old structure. Due to settling, the daymark was replaced with a lighted buoy in 1913. Most of the old structure was removed in 1925 by a buoy tender's derrick.

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