Francis Talbot may refer to:
Francis Talbot, 5th Earl of Shrewsbury (1500–1560), son of George Talbot, 4th Earl of Shrewsbury and Anne Hastings Francis Talbot, 11th Earl of Shrewsbury (1623–1668), English peer, second son of the 10th Earl of Shrewsbury Francis X. Talbot (1889–1953), American Jesuit publisher and academic administrator Manitonquat (1929–2018), Francis Talbot a.k.a. "Manitonquat" a.k.a. "Medicine Story", American New Age author and lecturer
See also Frances Talbot (disambiguation)