Thomas Middleton (1580–1627) was an English playwright.
Thomas Middleton may also refer to:
Thomas Middleton (died 1429), MP for Southampton Thomas Myddelton (Lord Mayor of London) (1550–1631) Thomas Myddelton (younger) (1586–1666), Welsh politician, parliamentarian soldier during the English Civil War Thomas Middleton (Sussex) (1589–1662), English politician who sat in the House of Commons variously between 1640 and 1660 Sir Thomas Middleton (1654–1702), MP for Harwich Thomas Middleton (1676–1715), MP for Essex Thomas Middleton (bishop) (1769–1822), Anglican bishop in India Thomas Cooke Middleton (1842–1923), American priest Sir Thomas Middleton (agriculturalist) (1863–1943), British biologist Thomas Percy Middleton (1893–?), British flying ace of World War I Thomas M. Middleton (born 1945), American politician from Maryland
See also Thomas Middleton Raysor (1895–1974), American literary scholar Tom Middleton (disambiguation) Thomas Myddelton (disambiguation)