Diego Rodríguez may refer to:
Politicians Diego Rodríguez Porcelos (died 885), son and successor of Rodrigo, count of Castile Diego Sinhué Rodríguez Vallejo (born 1980), Mexican politician, governor of Guanajuato (since 2018) Diego Rodriguez (Arizona politician), U.S. politician, Arizona State Representative
Sportspeople Diego Rodríguez (footballer, born 1960), Spanish football defender Diego Rodríguez (footballer, born 1986), Uruguayan football left-back Diego Rodríguez (footballer, born 1988) (1988–2010), Uruguayan football defender Diego Rodríguez (footballer, born 1989), Uruguayan football defensive midfielder Diego Rodríguez (goalkeeper) (born 1989), Argentine football goalkeeper Diego Rodríguez (footballer, born 1991), Uruguayan football defender Diego Rodríguez (footballer, born 1995), Honduran football left-back
Other Diego Rodríguez (mathematician) (1569–1668), mathematician, astronomer, educator and technological innovator in New Spain Diego Rodríguez (son of El Cid) (died 1097), died during the Battle of Consuegra
See also Diogo Rodrigues (died 1577), Portuguese explorer Diego Rodrigues (born 2005), Portuguese footballer