Ladysmith may refer to:

Ladysmith, KwaZulu-Natal, South Africa Ladysmith, British Columbia, Canada Ladysmith, Wisconsin, United States Ladysmith, New South Wales, Australia Ladysmith, Virginia, United States Ladysmith Island, Queensland, Australia, an island in Smith Islands National Park

Other Ladysmith (novel), a 1999 novel by Giles Foden Ladysmith Black Mambazo, a South African choral group Siege of Ladysmith (South Africa), 1900 Smith & Wesson Ladysmith, a small handgun

See also Lady Smith (disambiguation) List of people with surname Smith Ladismith, Western Cape, South Africa