VSC may refer to:

Organizations Venezuela Solidarity Campaign, a British political group Vermont State Colleges, the U.S. state of Vermont's system of public colleges Victory Services Club, a London private members' club for the armed forces Vietnam Solidarity Campaign, a Vietnam War-era activist group Volunteer Special Constabulary, a component of the Singapore Police Force Video Standards Council, of the UK responsible for promoting standards in the video industry Volunteer Service Corp, at Wake Forest University

Places Valley Stream Central High School, in Valley Stream, NY, US Vermont Studio Center, a fine arts and writing residency program located at Johnson in the US state of Vermont Vinings, Smyrna, Cumberland, an area in metropolitan Atlanta, US; See Vinings, Georgia

Science and technology Variable structure control, a type of discontinuous nonlinear control Variations in sex characteristics, congenital conditions Vertical service code, a special telephone number that usually begins with the * (star) key Vehicle Stability Control, Toyota's tradename for electronic stability control Video spectral comparator, a lighting instrument used in questioned document examination Volatile sulfur compounds, in organic chemistry Voltage source converter, a type of power electronics device

Computing Volume Shadow Copy Service, a mechanism of the NTFS file system Virtualization Service Client, software used to run Microsoft App-V virtualization software .vsc, a file extension used by the Versus programming language and the Viscosity image and animation editing utility Visual Studio Code, a Microsoft source code editor for Windows, Linux and macOS

Sport Debreceni VSC, a Hungarian football club Vitória Sport Clube, a Portuguese football club Vaipuna SC, an association football club in Samoa Virtual Safety Car, in motorsport

Other uses Aerovías Especiales de Carga (ICAO airline designator), a Colombian airline operator Vancouver Sleep Clinic, an Australian band Vehicle service contract, used for automotive repair, for example see Carchex

Vertebral subluxation complex, in chiropractic Vessel Safety Checks, of recreational boaters; See Missions of the United States Coast Guard