Wise guy or Wiseguy may refer to:

Film and TV Wiseguy (TV series), a US television series The Wise Guy, a 1926 silent crime drama film directed by Frank Lloyd The Wise Guys, a 1965 French comedy film directed by Robert Enrico Wise Guys (1961 film), directed by Claude Chabrol Wise Guys (1986 film), directed by Brian De Palma Wise Guy: David Chase and the Sopranos, a 2024 documentary film The Alto Knights, a 2025 film known during the production as Wise Guys

Music Wise Guys (band), a German a cappella group The Wiseguys, a British electronica hip hop band "Wise Guy", a 1998 song by Joe Pesci, from the album Vincent LaGuardia Gambini Sings Just for You Wise Guys (album), a 1998 album by Ghetto Commission Tropical Gangsters, a 1982 album by Kid Creole and the Coconuts, released in the US as Wise Guy

Other Wise Guy (musical), an unproduced musical by Irving Berlin Wise Guys, a Stephen Sondheim musical later renamed Road Show Wiseguy (The Simpsons), a fictional character on The Simpsons Wiseguy (book), a 1986 nonfiction book by Nicholas Pileggi that was the basis for the film Goodfellas Made man, an official member of the Mafia

See also Wise man Smart aleck (disambiguation)