Antietam may refer to:
Places Maryland Antietam, Maryland, an unincorporated community four miles south of the battlefield of the Battle of Antietam Antietam Iron Furnace Site and Antietam Village Antietam Hall Antietam Creek, a tributary of the Potomac River in Pennsylvania and Western Maryland; source name for the battle Antietam National Battlefield, an American national park
Pennsylvania Antietam Creek (Schuylkill River), a tributary of the Schuylkill River Antietam Lake, a reservoir in Berks County
Arts, entertainment, games and media Antietam (band), US indie rock band "Antietam", a song by Billy Corgan Antietam: The Bloodiest Day, 17 September 1862, a 1975 board wargame that simulates the American Civil War Battle Battleground 5: Antietam, a strategy computer game Sid Meier's Antietam!, a tactical computer game
Military Battle of Antietam, a major American Civil War battle Maryland Campaign, also known as the Antietam Campaign, an American Civil War invasion , three US Navy ships