50th Brigade or 50th Infantry Brigade may refer to:

Greece 50th Mechanized Infantry Brigade (Greece)

India 50th Indian Brigade of the British Indian Army in the First World War 50th Parachute Brigade (India) 50th Indian Tank Brigade

Russia/Soviet Union 50th Separate Operational Brigade

United Kingdom 50th Brigade (United Kingdom) 50th Light Anti-Aircraft Brigade (United Kingdom) 50th (South African) Brigade, Royal Garrison Artillery

United States 50th Infantry Brigade Combat Team (United States)

See also 50th Division (disambiguation) 50th Regiment (disambiguation)