5B or 5-B may refer to:
Entertainment Studio 5-B, a 1989 short-lived drama series about a Canadian TV news channel 5B (film), a 2018 documentary about the AIDS crisis by Dan Krauss and Paul Haggis BFDIA 5b, an episode of Battle for Dream Island which is a game.
Numbers and computing 5B is hexadecimal for 91 (number) 5B is the ASCII code for "[" Thus, %5B is URL encoding for "["
Space and space exploration Corot-Exo-5b, an extrasolar planet WASP-5b, an extrasolar planet Little Joe 5B, an unmanned Launch Escape System test of the Mercury spacecraft
Other uses Boron (5B), a chemical element 5B, the aircraft registration prefix for Cyprus
See also B5 (disambiguation)