A52 may refer to:
Roads A52 road (England), a road connecting Newcastle-under-Lyme and Mablethorpe A52 motorway (France), a road connecting Aubagne and the A50 Bundesautobahn 52, a highway in Germany usually referred to as A52 A52 motorway (Italy), a ring road around Milan A52 motorway (Switzerland), a road connecting Zumikon and Hinwil Autovía A-52 Spain, highway connecting Benavente and O Porriño
Other uses Samsung Galaxy A52, an Android smartphone The A/52 audio codec, also known as AC-3 or Dolby Digital Budapest Gambit, in chess (Encyclopaedia of Chess Openings code A52, among others) Action 52, a video game developed by Active Enterprises Ubiquitin A-52 residue ribosomal protein fusion product 1, a human gene