LTSA may refer to:

Local tangent space alignment, a nonlinear dimensionality reduction method Land Title and Survey Authority in British Columbia, Canada Land Transport Safety Authority, a former government entity in New Zealand, preceding Land Transport New Zealand Latin Tropical/Salsa Airplay, a Billboard music chart Lyceum Tourism Students Association, of Lyceum of the Philippines University Labelled Transition System Analyser, a verification tool for concurrent computer systems Long Term Service Agreement, an agreement to provide service over a number of years Last Time Seen Alive