B54 or B-54 may refer to: B54 (New York City bus), a bus line in Brooklyn Blackburn B-54, a British carrier-borne anti-submarine warfare aircraft Boeing B-54, an American strategic bomber aircraft Bundesstraße 54, a German road HLA-B54, an HLA-B serotype W54 nuclear warhead, which in one configuration was known as the B54 Special Atomic Demolition Munition (SADM)