2-Amino-4-hydroxy-6-pyrophosphoryl-methylpteridine (7,8-Dihydropterin pyrophosphate, dihydropterin-CH2OH-diphosphate) is a pteridine; a precursor to dihydrofolic acid.
Biosynthesis The enzyme 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase converts 6-hydroxymethyl-7,8-dihydropterin to 2-amino-4-hydroxy-6-pyrophosphoryl-methylpteridine by transferring a pyrophosphate group from the cofactor, adenosine triphosphate (ATP).
In organisms including Escherichia coli and Pneumocystis carinii this is a step in the biosynthesis of dihydrofolic acid. References