Preen may refer to:

Birds Preening, personal grooming of a bird's feathers especially by using its beak Preen gland, also called the uropygial gland, an oil gland found in many bird species

Products Preen, a trade name for trifluralin

Surname Garyn Preen (born 1991), Welsh footballer Alan Preen (born 1935), former sportsman who played Australian rules football