A clot is the final product of the blood coagulation step in hemostasis.

Clot may also refer to:

Blood Clot Boy, a figure in Native American folklore Clot (Barcelona Metro), a Barcelona Metro station El Clot-Aragó, the adjacent railway station Clotted cream In the United Kingdom, South Africa, and many other English-speaking countries, a foolish person

People with the surname Alexandre Clot (born 1972), Swiss footballer André Clot (1909–2002), French historian and essayist Antoine Clot (1793–1868), French physician Auguste Clot (1858–1936), French art printer