The following highways are numbered 425:
Canada Manitoba Provincial Road 425 New Brunswick Route 425 Newfoundland and Labrador Route 425 Ontario Highway 425
Japan Japan National Route 425
United States Interstate 425 (former) U.S. Route 425 Florida State Road 425 County Road 425 (Orange County, Florida) County Road 425 (Seminole County, Florida) Kentucky Route 425 Louisiana Highway 425 (former) Maryland Route 425 Nevada State Route 425 New York State Route 425 Pennsylvania Route 425 Puerto Rico Highway 425 Texas: Texas State Highway Loop 425 (former) Texas State Highway Spur 425 (former) Texas Farm to Market Road 425 Virginia State Route 425 (former)