Tuohy () is an Irish surname, derived from the Gaelic "Ó Tuathaigh", meaning "descendant of Tuathach", a personal name referring to a ruler or chieftain.

Notable people with the surname include:

Dan Tuohy (born 1985), Irish rugby player Denis Tuohy (born 1937), television broadcaster, actor, newsreader, and journalist Edward Tuohy (1908–1959), inventor of the Tuohy needle John S. Tuohy, brigadier general in the United States Air Force Katelyn Tuohy (born 2002) high school distance running record holder Leigh Anne Tuohy (born 1960), American businesswoman and interior decorator, portrayed in the film The Blind Side Liam Tuohy (footballer) (born 1933), Irish footballer and manager Owen Tuohy (1921–2007), Irish fencer Patrick Tuohy (1894–1930), Irish painter Sean Tuohy (born c. 1960), American sports commentator, restaurateur and former college basketball player, husband of Leigh Anne Tuohy Tom Tuohy (1917–2008), noted for putting out a major fire in Britain's worst nuclear accident William Tuohy, American Pulitzer Prize–winning journalist and author Zach Tuohy (born 1989), Australian rules football player

See also Tooey (disambiguation) Touhy (disambiguation)