Grilli is a surname. Notable people with the surname include:
Francesca Grilli (born 1978), Italian visual artist Guido Grilli (born 1939), American baseball relief pitcher Jason Grilli (born 1976), American baseball relief pitcher Julia V. Grilli (1893–1991), American lawyer and concert singer Paolo Grilli (1857–1952), Italian sculptor and painter Rodrigo-Antonio Grilli (born 1979), Brazilian tennis player Steve Grilli (born 1949), American baseball pitcher, father of Jason Vittorio Grilli (born 1957), Italian economist and academic
See also Grilli, Gavorrano, village in Tuscany