Hesselbach can refer to:
People
Franz Kaspar Hesselbach (1759-1816), German surgeon and anatomist Adam Kaspar Hesselbach (1788-1856), German surgeon and anatomist Jürgen Hesselbach, German professor and president of the Technical University of Braunschweig
Places in Germany
Hesselbach, Bad Laasphe, in North Rhine-Westphalia