Ice-nine is a fictional solid polymorph of water from Kurt Vonnegut's novel, Cat's Cradle.

Ice-nine may also refer to:

Ice IX, a form of solid water stable at temperatures below 140 K Ice Nine (video game), a first-person shooter video game for the Game Boy Advance ICE-9, a fictional computer virus in the American science fiction crime drama television series Person of Interest

Music "Ice 9", the second track on Joe Satriani's 1987 album, Surfing with the Alien ICE-9 (album), an instrumental album by Susumu Hirasawa Kerach 9 (English: Ice 9), an Israeli Rock band Lyod 9 (English: Ice 9), a 2001 album by Russian rock band Smyslovye Gallyutsinatsii Ice Nine Publishing, music publishers for the Grateful Dead 9ice, Nigerian musician, songwriter and dancer Ice Nine Kills, an American heavy metal band

Television ICE-9, a fictional computer virus in the American science fiction crime drama television series Person of Interest

Video Games Ice Nine, a first-person shooter video game for the Game Boy Advance Ice-9, a substance similar to the Cat's Cradle element used as a plot point in the video game 999: Nine Hours, Nine Persons, Nine Doors, described as "a special form of ice does not melt at room temperature", which is the subject of an in-game urban legend about an Egyptian priestess whose body was preserved in the substance and stored as cargo on the RMS Titanic