Mary Cook may refer to:
People Dame Mary Cook (1863–1950), wife of Australian prime minister Sir Joseph Cook Mary N. Cook (born 1951), American religious leader of the Young Women in the LDS Church Mary Pilcher-Cook (born 1954), American politician, member of the Kansas Senate Mary Virginia Cook Parrish (1862–1945), American educator, public speaker, and Black Baptist women's leader Mary Alexander Cook (1902–1981), museum curator and expert on Cape Dutch architecture Mary Curnock Cook (born 1958), British academic administrator Mary Elizabeth Cook (1863–1951), American artist Mary Ellen Cook (born 1980), American film star Mary Carey who ran for California governor in 2003
Other Mary Cook, original name of American screw steamer Mary L. Cook Public Library in Waynesville, Ohio