A cockatrice is a legendary creature resembling a large rooster with a lizard-like tail.

Cockatrice may also refer to:

Cockatrice (Dungeons & Dragons), a small avian magical beast in the role-playing game Dungeons & Dragons HMS Cockatrice, eight ships of the Royal Navy Cockatrice, a British armoured vehicle mounting a Lagonda flamethrower Cockatrice, open-source freeware used to play card games such as Magic: The Gathering over a network

See also Coquatrix, a French surname variant Cockentrice, a food