James Island may refer to:

James Island (Gambia), a World Heritage island in the Gambia James Island (British Columbia), an island in Haro Strait off Sidney, BC near Vancouver Island James Island (Galápagos), another name for Santiago Island (Galápagos) James Island (Maryland), an island in Chesapeake Bay James Island (South Carolina), an island near Charleston, South Carolina James Island (San Juan Islands), one of the San Juan Islands in Washington James Island (Washington), near La Push, Washington James Island (Chile) James Island (sanctuary), island of India James Island, a name for Baffin Island used by 18th-century French cartographers