Guccione is an Italian language surname, which is derived from the given name Guccio.Dictionary of American Family Names. "Guccione Family History", Oxford University Press, 2013. Retrieved on 21 January 2016. The name may refer to:

Bob Guccione (1930–2010), American magazine publisher Bob Guccione, Jr. (born 1955), American magazine publisher Chris Guccione (tennis) (born 1985), Australian tennis player Chris Guccione (umpire) (born 1974), American baseball umpire José Guccione (1952–2021), Argentine politician and physician Juanita Guccione (née Anita Rice; 1904–1999), American painter and taxidermist

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