O'Donohue is a surname, and may refer to: Becky O'Donohue (born 1980), reality television participant Daniel Anthony O'Donohue (1931–2019), United States Ambassador to Burma Edward O'Donohue (born 1974), Australian politician Jessie O'Donohue (born 1980), reality television participant John O'Donohue (1956–2008), poet and philosopher John F. O'Donohue (1946–2026), American actor Michael O'Donohue (1835–1912), Irish-American builder and architect Peter O'Donohue (1923–2012), Australian rules footballer Ryan O'Donohue (born 1984), American voice actor Tony O'Donohue (1933–2022), Irish-born Canadian politician William O'Donohue (born 1957), American psychologist
See also O'Donoghue Donohue