Duignan (, archaicly Ó Duibhgeannáin) is an Irish surname, and may refer to:
Noel Duignan (born 1948), Canadian politician Packie Duignan (died 1992), Irish flute player Michael Duignan (born 1968), Irish hurling manager Michael Duignan (bishop) (born 1970), Irish Catholic bishop Seán Duignan (born 1936), Irish journalist Dr John Duignan (born 1946), Scottish writer
See also Ó Duibhgeannáin