Mandrake is a poisonous herbaceous plant in the genus Mandragora, often connected with magical rituals.

Mandrake may also refer to:

Biology Mandragora (genus), a genus in the family Solanaceae, including Mandragora autumnalis, mandrake or autumn mandrake (considered by some sources to be a synonym of Mandragora officinarum) Mandragora caulescens, Himalayan mandrake Mandragora officinarum, mandrake or Mediterranean mandrake Mandragora turcomanica, Turkmenian mandrake Bryonia alba, English mandrake or white bryony Podophyllum peltatum, American mandrake, a North American plant in the family Berberidaceae

Arts and entertainment Film, television, and drama The Mandrake, a play by Niccolò Machiavelli first published in 1524 The Mandrake (1965 film), a 1965 Franco-Italian film Mandrake (TV series), a Latin American TV series Mandrake (1979 film), an American television thriller film Mandrake, a 2010 television film with Andrew Stevens Mandrake, an Indian Malayalam-language film series, consisting of Junior Mandrake (1997) Senior Mandrake (2010)

Fictional characters Mandragora (demon), a supernatural being in folklore Mandrake, a short-lived mascot at the University of Oregon Mandrake the Magician, a comic strip character Caleb Mandrake, a character in The Skulls, a feature-length film by Rob Cohen Group Captain Lionel Mandrake, a character in Stanley Kubrick's film Dr. Strangelove John Mandrake (Nathaniel), a character from the Bartimaeus Trilogy Paolo Mandrake, the lawyer and amateur detective who is the protagonist of stories by Rubem Fonseca, and basis for the TV series Mandrake, a character in the animated feature Epic

Music "Mandrake", a 1976 song on Gong's Shamal Mandrake (album), a 2001 album by Edguy Mandrake (German band), a gothic metal band Mandrake (Japanese band), a progressive rock band The Mandrake (band), an American death metal band The Mandrake Project, a 2024 album by Bruce Dickinson

Literature and publishing Mandrake of Oxford, a small press Mandrake Press, a publishing company The Mandrake (Surrealist group), a 20th-century Chilean Surrealist group

People Leon Mandrake (1911–1993), magician Tom Mandrake (born 1956), comic book artist

Other uses Mandrake Linux, former name of Mandriva Linux, a computer operating system Yakovlev Yak-25 (NATO designation: Mandrake), a Soviet aircraft Slang name for the recreational drug methaqualone

See also Mandarake, a Japanese retail corporation