Van Zile is a surname. Notable people with the name include:
Caroline Van Zile, American lawyer and politician Edward Sims Van Zile (1863–1931), American writer Jessie Van Zile Belden (1857–1910) American novelist Philip T. Van Zile (1843–1919), American politician and judge from Michigan
See also Van Zile House, 1736 house in Midland Park, Bergen County, New Jersey, United States