First State Bank or First State Bank Building may refer to several institutions and structures in the United States:
Bank systems First State Bank (Nebraska), now Dayspring Bank, a regional community bank system
Bank buildings Alphabetical by state, then town First State Bank of Manlius, Illinois, listed on the National Register of Historic Places (NRHP) First State Bank (Edna, Kansas), NRHP-listed Mitchell Building-First State Bank Building, Barbourville, Kentucky, NRHP-listed First State Bank of Le Roy, Minnesota, NRHP-listed First State Bank (St. Joseph, Minnesota), NRHP-listed First State Bank of Chester, Montana, NRHP-listed First State Bank, Dowling and Emhoff Buildings, Stevensville, Montana, NRHP-listed in Ravalli County First State Bank of Bethany, Lincoln, Nebraska, NRHP-listed in Lancaster County First State Bank of Buxton, North Dakota, NRHP-listed First State Bank of Indiahoma, Oklahoma, NRHP-listed in Comanche County First State Bank of Maramec, Oklahoma, NRHP-listed in Pawnee County First State Bank (Shattuck, Oklahoma), NRHP-listed in Ellis County First State Bank of Hazel, South Dakota, NRHP-listed First State Bank Building (Revillo, South Dakota), NRHP-listed First State Bank and Trust Building, Bryan, Texas, NRHP-listed in Brazos County First State Bank of Baggs, Wyoming, NRHP-listed Carey Block, also known as First State Bank of Greybull, Wyoming, NRHP-listed