Mississippi River Bridge may refer to:
Mississippi River Bridge (I-35W) or I-35W Mississippi River bridge, a bridge in Minnesota that collapsed in 2007 Mississippi River Bridge (Vicksburg, Mississippi) or Old Vicksburg Bridge Mississippi River Bridge (La Crosse, Wisconsin)
See also Lists of crossings of the Mississippi River New Mississippi River Bridge or Stan Musial Veterans Memorial Bridge, a bridge between St. Clair County and St. Louis