Deadly Duo may refer to:
The Deadly Duo, 1971 Hong Kong Wuxia film Deadly Duo (film), 1962 American neo noir directed by Reginald Le Borg "Deadly Duo", an episode of the 2019 Indian animated series Chacha Chaudhary
See also The Deadly Double, a board game released in November 1941, infamous for claims that the game's advertisements contained coded messages to secret agents, giving advance notice of the Pearl Harbor attack in December 1941