Henningsen is a patronymic surname, created from the given name Henning. Notable people with the surname include:
Agnes Henningsen (1868–1962), Danish writer and activist Alfred Meyer Henningsen (1918–2012), Norwegian politician Ann Margarit Henningsen (born 1949), Mexican sprint canoer Casper Henningsen (born 1985), Danish footballer and business executive Charles Frederick Henningsen (1815–1877), Belgian-American writer and military figure Erik Henningsen (1855–1930), Danish painter and illustrator Erika Henningsen (born 1992), American actress Frants Henningsen (1850–1908), Danish painter and illustrator Frits Henningsen (1889–1965), Danish furniture designer and cabinetmaker Inge Henningsen (born 1941), Danish statistician Jan Henningsen (born 1954), Danish motorcycle racer Juliane Henningsen (born 1984), Danish politician Matt Henningsen (born 1999), American football player Otto Henningsen (1883–1961), American politician Poul Henningsen (1894–1967), Danish architect and writer Thorkild Henningsen (1884–1931), Danish architect
See also Henningsen v. Bloomfield Motors, Inc.