SBO may refer to:
Jawa Pos TV, a television station in Surabaya, Indonesia formerly known as SBO TV SAP Business One, an enterprise resource planning software Senior British Officer, see Group captain Small bowel obstruction, a blockage of normal passage of digested food through the small intestine Small business owner, small business activities Sommers-Bausch Observatory, an astronomical observatory on the University of Colorado Boulder campus Stay-behind operation or Stay-behind organization Systems Biology Ontology, a project for the development of Systems Biology-oriented vocabularies and ontologies Tougeki – Super Battle Opera, a Japanese fighting video game tournament