Melkonian or Melkonyan () is a common family name of Armenian origin, literally meaning "son of Melkon" ("Melkon" is an Armenian given name).
It may refer to:
People Agop Melkonyan (1949–2006), Bulgarian writer Armen Melkonian, Armenian diplomat and career member of the Armenian Foreign Service Ashot Melkonian (1930–2009), Armenian artist Ashot Melkonyan (born 1961), Armenian historian, professor and academic advisor Babken Melkonyan (born 1980), Armenian snooker and pool player Gennadi Melkonian (1944–2002), Soviet and Armenian film director Harry Melkonian, Armenian American Law Professor James Melkonian (born 1961), American screenwriter and film director Karen Melkonyan (born 1999), Armenian footballer Lois Melkonian, former radio host and colleague of Dave Logan Markar Melkonian, scholar, brother of Monte Melkonian Melkon Melkonian, vice president of the Bulgarian Supreme Court Michael Melkonian (born 1948), German botanist Monte Melkonian (1957–1993), Armenian military commander Philippe Melkonian, musician, Clearlight bandmember Samvel Melkonyan (born 1984), Armenian football player Sirak Melkonian (1930–2024), Iranian-Armenian modernist painter Vartan Melkonian, British conductor of Lebanese-Armenian origin
Organizations Melkonian Educational Institute, a school in Cyprus Monte Melkonian Fund, a California-registered charity organization