Karst as a surname may refer to one of the following persons.

Friedrich Karst (1893–1975), German highly decorated Generalleutnant in the Wehrmacht Gene Karst (1906–2004), American, first dedicated publicist in the history of MLB John Karst (1893–1976) American professional baseball player Kenneth L. Karst (1929–2019), American legal scholar Michael Karst (born 1952), German track and field athlete Raymond W. Karst (1908–1987), an American former member of the United States House of Representatives See also P.Karst, a standard abbreviation for Petter Adolf Karsten