John Penn may refer to:
Descendants of William Penn, 1st proprietor of Pennsylvania: John Penn ("the American") (1700–1746), son of William Penn, 2nd proprietor of Pennsylvania, inherited 50% interest in Colony, died childless John Penn (governor) (1729–1795), son of Richard Penn, Sr. and grandson of William Penn, colonial governor of Pennsylvania, his 25% interest in the Colony was lost in the American Revolution John Penn (writer) (1760–1834), also called John Penn of Stoke, son of Thomas Penn and grandson of William Penn, 5th proprietor of Pennsylvania, his 75% interest in the Colony was lost in the American Revolution John Penn (North Carolina politician) (1741–1788), Continental Congressman from North Carolina, signer of the Declaration of Independence John Penn (engineer) (1805–1878), British marine engine engineer John Penn (Conservative politician) (1848–1903), MP for Lewisham 1891–1903 John Penn (architect) (1921–2007), British architect John Garrett Penn (1932–2007), United States federal judge John S. Penn (born 1926), American politician the New Jersey General Assembly John Penne, MP for Melcombe Regis
See also Jack Penn (1909–1996), South African surgeon