Greenville (formerly, Oregon Hill) is a former settlement in Yuba County, California, United States. It was located on Little Oregon Creek, southeast of Challenge, at an elevation of 2182 feet (665 m).

A post office operated at Greenville from 1857 to 1860.

In the late nineteenth century, Greenville had several hundred residents, a store, and a school. A narrow-gauge logging railroad connecting Challenge with the nearby Beanville Mill stopped in Greenville. By 1957, Greenville was essentially a ghost town.

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