San Andreas is an archaic variation of the Spanish language San Andrés (Saint Andrew, the apostle).

It may also refer to:

Places San Andreas, California, an unincorporated town San Andreas Fault, a geologic fault that runs through California San Andreas Lake, a lake near San Francisco, California for which the fault is named

Arts, entertainment, and media San Andreas (novel), a 1984 novel by Alistair MacLean San Andreas (film), a 2015 film directed by Brad Peyton San Andreas, a fictional location in several games in the Grand Theft Auto series San Andreas, a city based on San Francisco in the first Grand Theft Auto San Andreas, a state based on several parts of the Southwestern United States in Grand Theft Auto: San Andreas San Andreas, a state based on California in Grand Theft Auto V

See also San Andrés (disambiguation) St Andrews (disambiguation)