Biffo may refer to:
Biffo the Bear, a character in the British comic The Beano Paul Rose (writer) (born 1971), a.k.a. Mr. Biffo, games magazine editor, writer of a column named "Biffovision" Dave "Biffo" Beech, drummer/vocalist in British bands The Mighty Avengers and Jigsaw John Bindon (1943–1993), British actor and gangster A pejorative nickname for someone from County Offaly, Ireland particularly associated with Irish politician Brian Cowen