Zedler is a German surname. Notable people with the surname include:

Johann Heinrich Zedler (1706–1751), publisher of a German encyclopedia Gottfried Zedler (1860–1945), German historian and librarian Bill Zedler (born 1943), Republican member of the Texas House of Representatives Joy Zedler (born 1943), American ecologist Harry Zedler (born 1946), German footballer

See also Zeidler