Cruikshank ( ) is a surname of Scottish origin, and is a spelling variation of Cruickshank. Notable people with the surname include:
Andrew Cruikshank (1820–1859), Australian politician Brad Cruikshank (born 1979), Canadian ice hockey player Chester Cruikshank (1913–1970), American athlete Dale Cruikshank, American astronomer Dan Cruikshank (born 1949), architectural historian and broadcaster Dane Cruikshank (born 1995), American football player George Cruikshank (1792–1878), English caricaturist Holly Cruikshank (born 1973), American dancer Isaac Cruikshank (1756–1811), Scottish painter and caricaturist Isaac Robert Cruikshank (1789–1856), caricaturist, illustrator and portrait miniaturist Lucas Cruikshank (born 1993), web producer and creator of Fred Marcus Henderson Cruikshank (1826–1881), Confederate States of America politician Margaret Cruikshank (born 1940), American feminist writer and scholar Margaret Mordecai Jones Cruikshank (1878–1955), American academic administrator and teacher Robert Edward Cruickshank (1888–1961), Anglo-Canadian soldier, Victoria Cross recipient Sally Cruikshank (born 1949), American cartoonist and animator Thomas H. Cruikshank, American businessman William Cruikshank (disambiguation), several people
See also Crookshank Cruickshank 3531 Cruikshank, main-belt asteroid United States v. Cruikshank, 1876 US Supreme Court decision